منابع مشابه
Nitric Oxide in Asthma Physiopathology
Asthma is a chronic inflammatory airway disease characterized by allergen-induced airway hyperresponsiveness, airway inflammation, and remodeling. Nitric oxide (NO) derived from constitutive and inducible enzymes affects many aspects of asthma physiopathology. Animal in vivo studies have indicated that inhibition of iNOS may play a central role in the modulation of these features, particularly ...
متن کاملNitric Oxide in Asthma
Nitrogen monoxide, more commonly called nitric oxide or simply NO, is a fascinating free radical molecule, which participates in a broad range of important physiologic processes, including vasodilation, neurotransmission, and host defense. NO is generated from L -arginine by the enzyme nitric oxide synthase (NOS), of which there are three known isoforms. Types I and III NOS, found predominantly...
متن کاملNitric oxide and asthma.
Since nitric oxide (NO) was first described as endothelium derived relaxing factor (EDRF),I there has been compelling evidence that NO is involved in very many biological processes.2-9 It has at least four roles in the lungs.3 These are as a pulmonary vasodilator, bronchodilator, non-adrenergic non-cholinergic transmitter, and inflammatory mediator. There are three types of NO synthase, the enz...
متن کاملNitric oxide paradox in asthma.
Asthma results from allergen-driven intrapulmonary Th2 response, and is characterized by intermittent airway obstruction, airway hyperreactivity (AHR), and airway inflammation. Accumulating evidence indicates that inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO). It has been shown that exhaled NO may be derived from constitutiv...
متن کاملExhaled Nitric Oxide in Children with Asthma
1. Kharatonov SA, Barnes PJ. Exhaled markers of pulmonary disease. Am J Respir Crit Care Med. 2001;163:16931722. 2. Jouaville LF, Annesi-Maesano I, Nguyen LT, Bocage AS, Bedu M, Caillaud D. Interrelationship among asthma, atopy, rhinitis and exhaled nitric oxide in a populationbased sample of children. Clin Exp Allergy. 2003;33: 1506-11. 3. Wenzel SE. Asthma: defining of the persistent adult ph...
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ژورنال
عنوان ژورنال: ISRN Allergy
سال: 2011
ISSN: 2090-5521,2090-553X
DOI: 10.5402/2011/832560